Is intended use clearly communicated
As a mechanoenzyme, dynamin 2 (Dyn2) specifically engages in the terminal membrane scission phase of mitochondrial division following Drp1-mediated recruitment and oligomeric assembly at the OMM (Lee et al., 2016)
translocation from the endoplasmic reticulum to the Golgi, internalisation and recycling of the receptor.58, 59, 60, 61 The impact on many neuronal subtypes that are not CTR-expressing supports the notion that RAMPs interact with more GPCRs than just CTR-related family
Each product is manufactured under strict quality control conditions and rigorously tested for purity and consistency to ensure reliable and reproducible experimental results
It inhibits the production of pro-inflammatory cytokines (TNF-alpha, IL-6, IL-12), modulates the polarization of macrophages towards the M2 (anti-inflammatory) phenotype, and stimulates collagen production in models of pulmonary and cutaneous fibrosis